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 Add this item to the list  Penicillium marneffei Segretain
Page number:833 
Description type:Non-original description 
Description:Penicillium marneffei Segretain
Colony characteristics. Colonies (CzA, 30°C) flat, sparse, compact, greenish to purplish, on MEA exuding an orange or red pigment into the medium; primary cultures often canary yellow due to sterile aerial mycelium. At 37°C colonies restricted, whitish, yeast-like.
Microscopy. Hyphae in part spirally twisted. Conidiophores creeping or fasciculate, 70-150 x 2.5-3.0 µm; penicilli generally biverticillate but also irregularly monoverticillate or more complex. Metulae 7-11 µm long, in whorls of 3-5. Phialides in whorls of 4-7, ampulliform to acerose, 6-10 x 2.5-3.0 µm. Conidia smooth-walled, ellipsoidal, 2.5-4.0 x 2-3 µm, often with prominent scars, borne in short, disordered chains.
Physiology. An arthroconidial synanamorph ('yeast phase') is produced at 37°C.
Serology. Antigenic relationships were investigated by Sekhon et al. (1989). A specific fluorescent-antibody test was developed by Kaufman et al. (1995) and antigen detection by Kaufman et al. (1996), Desakorn et al. (1998) and Chaiyaroj et al. (2003).
Differential diagnosis. In vivo the species differs from Histoplasma (p. 708) by the occurrence of some septate and slightly curved cells in bone marrow smears (Wuning et al., 2002). Distinguished from Pneumocystis (p. 176) by positive Giemsa staining. In vitro the species shows poor growth and sporulation.
Distribution. Thailand and adjacent countries, Kampuchea ( Bailloud et al., 2002), Taiwan (Lin et al., 1998), India (Singh et al., 1999). Imported cases are common outside endemic areas. A possibly endemic case from Ghana (Africa) was reported by Lo et al. (2000)
References. Yayanetra et al. (1984), Deng et al. (1986), Mori et al. (1987), Qi et al. (1990), Chiewchanvit et al. (1991), Tsui et al. (1992), Drouhet (1993), Liu et al. (1994), Ajello et al. (1995), Wortman (1996), Vanittanakom & Sirisanthana (1997).
Nomenclature. Penicillium marneffei Segretain - Bull. Trim. Soc. Mycol. Fr. 75: 416, 1959.
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